1. Ammo
  3. Rifle Ammunition
  5. 22-250 Remington

22-250 Remington Ammunition for Sale

The .22-250 Remington excels at long-range varmint control and precision target work, pairing lightweight bullets—typically 35 to 55 grains—with a magnum rifle case for razor-flat trajectories and minimal recoil. Match-grade jacketed hollow points and polymer-tipped loads deliver explosive expansion on prairie dogs, coyotes and small predators, while full metal jacket rounds offer consistent accuracy for high-volume range sessions. Popular in bolt-action rifles and AR-style platforms, these cartridges feed reliably and ignite cleanly in both factory and handloaded brass. At Sportsman’s Outdoor Superstore, you’ll find .22-250 Rem ammo from leading manufacturers—compare bullet profiles, check in-stock availability and complete your purchase online with competitive pricing, secure checkout and fast shipping.
22-250 REM 50 GR JHP VARMINT/PREDATOR

Federal 22-250 Rem 50 gr JHP American Eagle Varmint and Predator 50/Box

  • $104.99 $58.68 ($1.17 / round )
In Stock
  • Brand: Federal
  • Item Number: AE2225050VP
  • Type: Hunting
  • Quantity: 50 Rounds
22-250 REM 40 GR HORNADY V-MAX BULK

Federal 22-250 Rem 40 Gr Hornady V-Max Bulk Pack 50/Box

  • $55.99 ($1.12 / round )
  • Brand: Federal
  • Item Number: V22250VM40B
  • Type: Hunting
  • Quantity: 50 Rounds
22-250 REM 50 GR V-MAX (50)

Hornady 22-250 Remington 50 gr V-MAX 50/Box

  • $42.99 ($0.86 / round )
  • Brand: Hornady
  • Item Number: 83361
  • Type: Hunting
  • Quantity: 50 Rounds
BRNS 22008 BB2225XFB1 22250 50 TSX FB 20/10

Barnes 22-250 Remington 50 Grain TSX Flat Base VOR-TX 20/Box

  • $39.04 ($1.95 / round )
In Stock
  • Brand: Barnes
  • Item Number: 22008
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 55 GR SPIRE POINT

Hornady 22-250 Rem 55 gr Spire Point 50/Rounds

  • $41.99 ($0.84 / round )
  • Brand: Hornady
  • Item Number: 83365
  • Type: Target
  • Quantity: 50 Rounds
22-250 REM 55 GR NOSLER BALLISTIC VITAL-SHOK

Federal 22-250 Rem 55 gr Nosler Ballistic Tip V-Shok 20/Box

  • $39.99 ($2.00 / round )
  • Brand: Federal
  • Item Number: P22250F
  • Type: Hunting
  • Quantity: 20 Rounds
HSM 2225020N 22250 55 BLITZKING 20/25

Hsm 22-250 Remington 55 Grain Sierra Blitz King 20/Box

  • $29.26 ($1.46 / round )
In Stock
  • Brand: Hsm
  • Item Number: 2225020N
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 40 GR VARMINT/PREDATOR

Sig Sauer 22-250 REM 40 gr Varmint and Predator Tip Elite Performance 20/Box

  • $37.99 ($1.90 / round )
  • Brand: Sig Sauer
  • Item Number: E222V1-20
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 55 GR BALLISTIC SILVERTIP

Winchester 22-250 Rem 55 gr Ballistic Silvertip 20/Box

  • $36.99 ($1.85 / round )
  • Brand: Winchester
  • Item Number: SCST22250B
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 45 GR JHP

Winchester 22-250 Rem 45 gr JHP 40/Box

  • $45.59 $52.38 ($1.31 / round )
In Stock
  • Brand: Winchester
  • Item Number: USA222502
  • Type: Hunting
  • Quantity: 40 Rounds
22-250 REM 55 GR FB TIPPED 20/BOX

Nosler 22-250 Rem 55 gr FB Tipped 20/Box

  • $45.59 $37.22 ($1.86 / round )
In Stock
  • Brand: Nosler
  • Item Number: 65155
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 55 GR BALLISTIC TIP VARMINT AMMUNITION 20/BOX

Nosler 22-250 Rem 55 gr Ballistic Tip Varmint Ammunition 20/Box

  • $45.59 $39.30 ($1.97 / round )
In Stock
  • Brand: Nosler
  • Item Number: 61034
  • Type: Hunting
  • Quantity: 20 Rounds
HSM 222504N 22250 55 SP 20/25

Hsm 22-250 Remington 50 Grain Soft Point Varmint 20/Box

  • $45.59 $24.20 ($1.21 / round )
In Stock
  • Brand: Hsm
  • Item Number: 222504N
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 60 GR NOSLER PARTITION VITAL-SHOK

Federal 22-250 Remingon 60 gr Nosler Partition Vital-Shok 20/Box

  • $38.95 $30.99 ($1.55 / round )
  • Brand: Federal
  • Item Number: P22250G
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 35 GR V-MAX SUPERFORMANCE VARMINT

Hornady 22-250 Rem 35 gr V-Max Superformance Varmint 20/Box

  • $35.04 $30.92 ($1.55 / round )
In Stock
  • Brand: Hornady
  • Item Number: 8334
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 43 GR SPEER TNT GREEN VITAL-SHOK

Federal 22-250 Rem 43 gr Speer TNT Green V-Shok 20/Box

  • $31.95 $29.99 ($1.50 / round )
  • Brand: Federal
  • Item Number: P22250D
  • Type: Hunting
  • Quantity: 20 Rounds
AMMO, 22250 REM, 40GR, ELITE SERIES VP, POLY TIP

Sig Sauer 22-250 Rem 40 gr Extreme Expansion Tip Elite Series Varmint and Predator 20/Box

  • $38.99 $28.03 ($1.40 / round )
In Stock
  • Brand: Sig Sauer
  • Item Number: E225VP40-20
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 50 GR V-MAX SUPERFORMANCE VARMINT

Hornady 22-250 Rem 50 gr V-Max Superformance Varmint 20/Box

  • $29.58 $27.99 ($1.40 / round )
In Stock
  • Brand: Hornady
  • Item Number: 83366
  • Type: Hunting
  • Quantity: 20 Rounds
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