The 221 Remington Fireball delivers exceptional downrange performance in a compact case tailored for short-action rifles and AR-platform conversions. Popular bullet weights from 35 to 50 grains suit everything from prairie dog control to steel-target competition, with polymer-tip and hollow-point offerings engineered for rapid expansion and surgical accuracy. Handloaders appreciate the consistent brass and moderate powder capacity, which allow fine-tuning of each load for optimal grouping. At Sportsman’s Outdoor Superstore, you’ll find 221 Rem Fireball ammo from top manufacturers—compare bullet designs, check real-time inventory, then complete your purchase online with competitive pricing, secure checkout and prompt shipping.